What is Osteoporosis?
Osteoporosis is a condition that makes bones become weak and brittle, making them more susceptible to fractures and breaks. It is most common in post-menopausal women, but it can also affect men and younger adults. Osteoporosis is caused by a lack of calcium and vitamin D, as well as lifestyle factors such as smoking, excessive alcohol consumption and a lack of exercise. As bones lose density, they become weaker and more fragile. This can lead to an increased risk of fractures and breaks, particularly in the spine, wrists, and hips.
What is Prolia?
Prolia is a medication used to treat osteoporosis. It is a type of monoclonal antibody, which means it works by binding to a specific protein in the body and stopping it from functioning. In this case, Prolia binds to and blocks the receptor activator of nuclear factor kappa-B ligand (RANKL), which is responsible for breaking down bone. By blocking this protein, Prolia helps to increase bone density and decrease the risk of fractures.
How Does Prolia Help Osteoporosis?
Prolia works by increasing bone density, which helps to reduce the risk of fractures. Studies have shown that Prolia can reduce the risk of spinal fractures by up to 70%, and hip fractures by up to 50%. The medication is usually given as an injection once every 6 months, and it is thought to be most effective when used in combination with other treatments such as calcium and vitamin D supplements.
Who Should Take Prolia?
Prolia is recommended for post-menopausal women who are at high risk of developing osteoporosis, such as those with a history of fractures. It is also recommended for post-menopausal women who have already been diagnosed with osteoporosis and are at high risk of developing fractures. Prolia is not recommended for men or younger adults, as it is not yet known if it is effective in treating osteoporosis in these groups.
What are the Side Effects of Prolia?
The most common side effects of Prolia include joint pain and muscle pain. Other side effects may include nausea, vomiting, constipation, diarrhea, and fatigue. More serious side effects may include an increased risk of infection or an allergic reaction. It is important to tell your doctor if you experience any of the above side effects.
Conclusion
Prolia is a medication used to treat osteoporosis in post-menopausal women who are at high risk of developing fractures. It works by increasing bone density and reducing the risk of fractures. Prolia is usually given as an injection once every 6 months, and it is most effective when used in combination with other treatments such as calcium and vitamin D supplements. Prolia can cause side effects, so it is important to talk to your doctor about the risks and benefits before starting the medication.
References
1. National Osteoporosis Foundation. (2020). What Is Osteoporosis?. Retrieved from https://www.nof.org/patients/what-is-osteoporosis/
2. National Institutes of Health. (2021). Prolia (Denosumab). Retrieved from https://www.nlm.nih.gov/medlineplus/druginfo/meds/a604009.html